The government appeals the district court’s order granting Robert Thomas Logan, Jr.’s motion to suppress evidence. We reverse and remand.
I
On July 18, 2000, Detective James Flynn of the Los Angeles Police Department was dispatched to Mail Box Services Plus, a commercial mail receiving agency (CMRA), in Sherman Oaks, California to investigate a suspicious package. Detective Flynn examined the package and determined it was being sent from the Los Angeles metropolitan area to Sound Masters, 6614 Clayton Rd., St. Louis, Missouri. The airbill carried the typewritten name and address of Mail Box Services Plus as sender and the handwritten name and address of Sound Masters as consignee. Flynn also noted the package was scheduled for second-day air delivery to Sound Masters in care of a St. Louis Mail Boxes Etc. facility. At Flynn’s request, a drug-sniffing dog was dispatched to the location and alerted on the package.
Detective Flynn has been in law enforcement since 1989. Since 1994, he has *532worked as a narcotics investigator for the LAPD and has extensive experience with the illegal drug trade. At the time of these events, Flynn was assigned to the LAPD’s parcel interdiction squad. Flynn testified he detained the package because, based on his extensive training and experience, it fit several characteristics of the profile used by law enforcement to interdict packages containing drugs. In particular, he testified Los Angeles is a source city for narcotics and St. Louis is a city to which drugs are frequently shipped. Flynn further testified drug traffickers commonly use second-day air delivery to ensure rapid reliable delivery and limit the time during which packages are exposed to possible detection. Additionally, he testified drug traffickers frequently ship packages via CMRAs to conceal the sender’s identity, and prefer to use handwritten labels that can be filled out moments before the package is deposited with the CMRA to further lessen the chances of detection. On cross-examination, Flynn testified second-day air delivery is one of six methods of shipment offered by FedEx, with priority next-day and standard next-day being faster. He acknowledged choosing second-day air delivery exposes a package to scrutiny for a longer period of time and his affidavit stated next-day air delivery is the normal method used by drug traffickers.
After the drug-sniffing dog alerted, police obtained a search warrant and found a stereo speaker inside the package containing approximately one kilogram of cocaine. The package was allowed to continue on to the St. Louis Mail Boxes Etc., where police arranged for a controlled delivery. In the process of arranging for the controlled delivery, police came across a second package bearing nearly the same characteristics as the first and arranged for a controlled delivery of both packages. Later that same day, Wendy Hull came to Mail Boxes Etc. and retrieved the packages. Police arrested her and subjected the second package to a dog sniff. After the dog alerted, police obtained a search warrant and discovered approximately one kilogram of cocaine hidden inside a stereo speaker.
A search of Hull’s person uncovered a mailing receipt for yet a third package which led to the seizure of a package containing $19,050 mailed from St. Louis to a Los Angeles CMRA. Hull cooperated with police and led them to Logan who was arrested and indicted on one count of possession of over 500 grams of cocaine with intent to distribute in violation of 21 U.S.C. § 841(a)(1).
Logan moved to suppress all the evidence arguing police did not have a reasonable suspicion based on articulable facts sufficient to detain the first package. Because the search of the first package led to discovery of the subsequent packages, Logan argued the evidence discovered in the second and third packages should also be suppressed. The magistrate judge recommended denying the motion, however, the district court rejected the recommendation and suppressed the evidence. The government moved for reconsideration arguing the seizure was justified because police had relied in good faith on the search warrant. The district court determined this argument, raised for the first time in the motion for reconsideration, had been waived. The government now appeals.
II
We review a district court’s decision to grant a suppression motion de novo while reviewing the underlying factual determinations for clear error. United States v. Walker, 324 F.3d 1032, 1036 (8th Cir.2003).
*533A. Seizure
The government first contends subjecting the package to a dog sniff was not a seizure requiring reasonable suspicion. We disagree. Under our existing precedent it is clear this package was seized for Fourth Amendment purposes when Detective Flynn detained it and subjected it to a canine sniff. See Walker, 324 F.3d at 1036 (holding a package was seized when it was “moved ... to a separate room for a canine sniff .... ”); United States v. Morones, 355 F.3d 1108, 1111 (8th Cir.2004) (holding a package was seized when it was removed from the mail stream and held for a dog sniff).
B. Reasonable Articulable Suspicion
Having concluded the package was seized we next consider whether the seizure was supported by a reasonable and articulable suspicion.
To support a seizure, “[l]aw enforcement authorities must possess a reasonable suspicion based on articulable facts that a package contains contraband before they may detain the package for investigation.” United States v. Johnson, 171 F.3d 601, 603 (8th Cir.1999) (citing United States v. Van Leeuwen, 397 U.S. 249, 252-53, 90 S.Ct. 1029, 25 L.Ed.2d 282 (1970)). “Reasonable suspicion exists when, based on the totality of the circumstances, an officer possesses a particularized and objective basis for suspecting that the package contains contraband, that is, more than an inchoate and unparticularized suspicion or hunch.” Id. (internal quotations and citation omitted). The reasonable articulable suspicion standard anticipates a fact-specific inquiry examining the totality of the circumstances informing a law enforcement officer’s determination of reasonable suspicion. Walker, 324 F.3d at 1037 (citing United States v. Terriques, 319 F.3d 1051, 1056 (8th Cir.2003)). Further, “[l]aw enforcement officers are permitted to draw ‘inferences and deductions that might well elude an untrained person.’ ” Johnson, 171 F.3d at 604 (quoting United States v. Cortez, 449 U.S. 411, 418, 101 S.Ct. 690, 66 L.Ed.2d 621 (1981)). The Fourth Amendment, however, requires police “to explain why the officer’s knowledge of particular criminal practices gives special significance to the apparently innocent facts observed.” Id. (citing Cortez, 449 U.S. at 418-22, 101 S.Ct. 690) (emphasis in original).
The district court determined the police failed to articulate a sufficient basis to warrant seizing the first package. Specifically, the district court noted Detective Flynn’s affidavit stated drug traffickers typically send packages by priority next-day or standard next-day delivery, but this package was sent second-day air delivery. Further, the district court pointed to the absence of evidence explaining why the Mail Box Services Plus employee believed the package was suspicious in the first instance. Finally, the district court distinguished this case from cases where reasonable suspicion had been established because in those cases there were additional characteristics supporting the finding, e.g., the package emitted a heavy odor of perfume, was marked fragile and heavily taped, bore an incorrect address, or the airbill account number was missing.
Detective Flynn articulated the following characteristics he determined were consistent with the drug-package profile: 1) the package was shipped from Los Angeles, a drug source city; 2) the package was shipped to St. Louis, a drug target city; 3) the package was shipped from a CMRA; 4) the package was shipped second-day air delivery; 5) the package was shipped to a CMRA; and 6) the name and address of the recipient were handwritten. Each of these factors, when considered *534alone, is consistent with innocent mail use. Our inquiry, however, does not require us to “rule out the possibility of innocent conduct.” Terriques, 319 F.3d at 1057 (quoting United States v. Arvizu, 534 U.S. 266, 276, 122 S.Ct. 744, 151 L.Ed.2d 740 (2002)). When viewed in the aggregate by a trained law enforcement officer these factors give rise to the objectively reasonable suspicion needed to justify a dog sniff. Detective Flynn, relying on his experience and training, explained the relevance of the independently insignificant facts, and, notwithstanding the distinction between next-day delivery and second-day delivery, demonstrated the reasonable suspicion required under the Fourth Amendment. Considering the totality of the circumstances, we find Detective Flynn had a reasonable suspicion based on articulable facts sufficient to detain the package and subject it to a dog sniff.
Ill
Accordingly, the district court’s suppression order is vacated and the case is remanded for further proceedings, including the denial of Logan’s motion to suppress.